In this post, I’ve made a brief summary of the main theories of aging. There are many theories to explain it.
I've looking for some information about free radical theory which is probably the most used. There are so much products have been developed for anti-aging and antioxidant diets based in this theory, for these reason I want to outline some points of free radicals theory as well as antioxidants.
First of all I want to describe the biologic theories, because we must know all of them. After this, I’ll try to explain something about free radicals theory.
There is no single universally accepted definition of aging. Theories of aging have been considered throughout recorded history as mankind has sought to find ways to avoid aging. Theories abound to explain and give some logical order to our observations. Observations, like theories, including physical and behavioural data, are collected and studied to scientifically prove or disprove their effects on aging.
Biologic theories, each theory attempts to describe the processes of aging by examining various changes in cell structures or function.
The programmed theory proposes that every person has a “biologic clock”
The rut- out- program theory: every person has a limited amount of genetic material that will run out over time.
The living theory: proposes that individuals have a finite number of breaths or heart- beats.
The gen theory proposes the existence of one or more harmful genes
The molecular theories: propose that aging is controlled by genetic materials
The error theory: Proposes that error in ribonucleic acid cause errors to occur in cells in the body.
The somatic mutations theory: Is similar but proposes that aging results from deoxyribonucleic acid ( DNA)
The free radical theory: I consider this is the most significant theory on aging, perhaps the most extended and applied at many anti-aging products.
The free radical theory provides a one explanation for cell damage. Free radicals are unstable molecules produces by the body during the normal metabolism or following exposure to radiation and pollution. These free radicals are suspected to cause damage to the cells, DNA, and the immune system. Excessive accumulations of free radicals are suspected to cause free damage to the cells, DNA, and the immune system. Excessive accumulation of free radicals in the body is purported to cause or contribute to the physiologic changes of aging and a variety of diseases .One free radical named lipofuscin, has been identify to cause a build up of fatty pigments granules that cause age spots in older adults. Individuals who support this theory propose that the number of free radicals can be reduced by the use of antioxidants such as vitamins A, C, and E carotenoids zinc, selenium, and phytochemicals.
I want to emphasize the activity of antioxidants and how they act on free radicals.
Antioxidants are substances that may protect cells against the effects of free radicals. Free radicals are molecules produced when body breaks down food, or by environmental exposures like tobacco smoke and radiation. Free radicals can damage cells, and may cause heart disease, cancer and other diseases.
Antioxidant substances include:
Beta-carotene
Lutein
Lycopene
Selenium
Vitamin A
Vitamin C
Vitamin E
Antioxidants are found in many foods. These include fruits and vegetables, nuts, grains, and some meats, poultry and fish.
I believe that we should give more importance to proper nutrition as well as the removal of certain toxic habits to provide an adequate supply of antioxidants to our organism. In the other information I’ve found is recommended taking supplements of vitamins C, E and D, at this respect, I disagree, perhaps because of my training as a nutritionist I don't think it's a required contribution, I think it's enough a diet of foods rich in these vitamins, the practice of regular exercise and the removal of smoking, this all can provide the necessary amounts of these vitamins.
The Antioxidants and Disease Prevention:
Heart Disease: Vitamin E may protect against cardiovascular disease by defending against LDL oxidation and artery-clogging plaque formation.
Cancer: Many studies have correlated high vitamin C intakes with low rates of cancer, particularly cancers of the mouth, larynx and esophagus.
Individuals who support this theory propose that the number of free radicals can be reduced by the use of antioxidants such as vitamins A, C and E, carotenoids, zinc selenium and phytochemicals.
This is the antioxidants therapy. Antioxidant therapy include dietary changes as well as specific dietary supplements generally, antioxidant supplements are seen as relatively safe. High doses of some antioxidants may cause more harm than benefits. Anti Aging Foods:
This is a brief list of antioxidant-riched food :
SALMON
OLIVE OIL
BROCCOLI
ACAI
BERRIES, CHERRIES and GRAPES
GARLIC AND ONIONS
This theory is the base of some products that treat the physical changes of aging.
Consulted bibliography and links:
http://www.healthchecksystems.com/antioxid.htm
http://www.nlm.nih.gov/medlineplus/antioxidants.html
AGING: A THEORY BASED ON FREE RADICAL AND RADIATION CHEMISTRY
DENHAM HARMAN, M.D., Ph.D.
The cross line: Also called connective tissue theory
The clinker theory: The clinker theory combines somatic mutation, free radicals, and crosslink theories to suggest that chemicals produced by metabolism
The neuroendocrine theory: The neuroendocrine theory focuses on the complicated of chemical interactions set off by the hypothalamus of the brain.
The immunologic theory: proposes that the increase in autoimmune diseases and allergies seen with aging is caused by changes in the immune system.
Guerra-Araiza C, Alvarez-Mejía AL, Sánchez-Torres S, Farfan-García E,Mondragón-Lozano R, Pinto-Almazan R, Salgado-Ceballos H. Effect of NaturalExogenous Antioxidants on Aging and on Neurodegenerative Diseases. Free RadicRes. 2013 Apr 18. [Epub ahead of print] PubMed PMID: 23594291.